AADB
Acid/Alkaline Resistance Gene Database
A curated, mechanism-oriented database of microbial genes and proteins involved in pH stress adaptation.
AADB is a curated resource for microbial acid and alkaline resistance genes organized at the gene/protein level. The database groups entries into 11 mechanism-linked functional systems and supports browsing, filtering, sequence similarity search, and downloadable structured outputs.
AADB currently supports protein sequence query in FASTA format through a BLAST-based search workflow.
Supported input:
- Single protein sequence
- Multiple protein sequences
- FASTA format only
Typical output:
- Matched AADB entries
- Functional system assignment
- Organism information
- Curated pH-related annotation
Example FASTA Input
>example_protein
MKKTAIAIAVALAGFATVAQAAP...BLAST Search
Identify candidate pH-resistance proteins using sequence similarity against the local AADB database.
Browse / Search
Filter entries by functional system, organism, gene name, keyword, or sequence length.
Functional Systems
Explore the 11 mechanism-oriented pH adaptation systems and their representative genes.
Download
Export FASTA sequences, metadata tables, and versioned database resources for downstream analysis.
The current AADB release contains curated non-redundant protein entries spanning multiple microbial taxa and pH adaptation mechanisms.
Entries by Functional System
Entries by Organism
Sequence Length Distribution
- Mechanism-oriented rather than organism-oriented
- Gene/protein-level curation for pH stress adaptation
- Sequence-to-mechanism mapping through BLAST
- Structured and downloadable release files for reproducible reuse